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AI Qualitative Analysis in Healthcare: PROMIS CATs

Evidano8 min read

Physical therapy researchers and healthcare teams often collect patient-reported outcomes, interviews, surveys, and implementation feedback at the same time. The challenge is converting that mixed-methods evidence into a reliable explanation of what works, what creates burden, and what clinicians and patients need next. AI qualitative analysis in healthcare can help research teams organize interview transcripts and open-ended responses, compare stakeholder perspectives, and identify themes without replacing methodological judgment. A November 13, 2026 study in PLOS One examined the feasibility of Dutch-Flemish PROMIS computerized adaptive tests, or CATs, in primary care physical therapy. The study combined a survey of 25 physical therapists with interviews involving 10 therapists and 9 patients across 14 practices. This article explains the study's findings, shows where qualitative analysis adds value, and outlines a practical AI-assisted workflow for healthcare researchers. The analysis is research-focused and non-diagnostic.

Key Takeaways

According to the November 13, 2026 PLOS One study, PROMIS CATs were feasible and generally acceptable in primary care physical therapy, but sustainable adoption depended on reducing duplicate questionnaires, improving score interpretation, and embedding the tools into clinical workflows.

AI qualitative analysis in healthcare can make mixed-methods evidence easier to synthesize by connecting survey patterns with interview themes, participant quotations, and differences between therapist and patient perspectives.

  • The PLOS One study surveyed 25 physical therapists and interviewed 10 physical therapists plus 9 patients across 14 practices in the Netherlands.
  • The study collected survey data between May 2 and June 20, 2022, and conducted interviews between March 21 and November 23, 2022.
  • According to the study, 80% of surveyed physical therapists were interested in using PROMIS CATs, while only 28% reported regular daily use.
  • According to the study, 100% of surveyed physical therapists found PROMIS CATs easy to administer, but only 40% believed the CATs took little time.
  • The study found a stakeholder divergence: only 24% of therapists believed patients were satisfied with CATs, while interviewed patients generally described CATs as quick, simple, and relevant.

How PROMIS CATs Were Evaluated in Physical Therapy

The PLOS One study evaluated PROMIS CAT feasibility through four domains: acceptability, demand, practicality, and implementation. The researchers used a concurrent mixed-methods design that combined a therapist survey with semi-structured interviews involving therapists and patients.

The study examined Dutch-Flemish PROMIS CATs for pain interference, physical function, and upper-extremity function among adults with musculoskeletal conditions affecting the spine or upper extremities. The CAT system selected questions dynamically, administered at least 4 and no more than 12 items, and stopped when a prespecified precision threshold was reached.

The PLOS One researchers analyzed interview transcripts through hybrid inductive-deductive thematic analysis. Two researchers independently open-coded transcripts, compared codes during consensus meetings, and used a third researcher to resolve disagreements when necessary. The research team mapped emergent themes onto Bowen's feasibility domains.

The study did not use AI qualitative analysis. The researchers used Atlas.ti software, human coding, consensus discussions, and peer debriefing. That distinction matters because AI can accelerate organizing and comparison, but healthcare researchers still need to validate interpretations against transcripts, study design, and participant context.

PROMIS CAT Findings Snapshot

Date or measureFinding reported by the PLOS One studyImplication for qualitative research
November 13, 2026The study was published in PLOS One.Researchers can use the publication as a current case study for mixed-methods implementation analysis.
Study setting14 primary care physical therapy practices in the Netherlands.Cross-site qualitative comparison can reveal whether workflow barriers are local or recurring.
Participants25 therapists completed the survey; 10 therapists and 9 patients were interviewed.The sample supports comparison between professional perceptions and patient accounts.
Acceptability76% of therapists agreed that CATs contributed to treatment evaluation, and 72% agreed that CATs improved quality of care.Thematic coding can explain why perceived clinical value did not always translate into routine use.
Demand80% of therapists expressed interest in using CATs, but 28% reported regular daily use.A frequency and cross-segment analysis can isolate the gap between intention and behavior.
Practicality96% found CATs easy to locate in the electronic health record, and 100% found them easy to administer.Researchers can separate technical usability from broader portal and workflow problems.
Implementation60% reported management support, while 24% reported mandatory use.Qualitative analysis can identify organizational conditions that influence adoption.

Implications for Healthcare Researchers and Physical Therapy Teams

What did therapists and patients value about PROMIS CATs?

The PLOS One study found that therapists and patients valued CATs because the adaptive format focused questions on the respondent's condition and could support conversations about symptoms and functioning.

One patient said, "Answering the questions made me reflect on my symptoms and what I want help with" (Patient #5). One therapist said, "The graph helps patients see their progress, even when symptoms are still there" (PT #2). These quotations show how qualitative evidence explains the mechanism behind the survey results.

What barriers limited routine implementation?

The PLOS One study identified duplicate legacy PROMs, patient-portal problems, uncertainty about T-scores and cut-offs, limited organizational embedding, and concerns about the relevance of some items as implementation barriers.

The study also reported that only 48% of therapists always or mostly discussed CAT results with patients. A qualitative coding workflow can distinguish barriers caused by the CAT itself from barriers caused by the surrounding digital and administrative system.

Why should researchers compare stakeholder segments?

The PLOS One study showed why therapist perceptions should not be treated as a substitute for patient evidence. Only 24% of therapists believed patients were satisfied with CATs, while interviewed patients generally described CATs as quick, simple, and relevant.

Cross-segment analysis can preserve this divergence rather than averaging it away. Researchers can compare patients, therapists, practice owners, and implementation leaders by theme frequency, representative quotations, and reported barriers.

What should implementation teams do next?

The PLOS One study recommended phasing out legacy PROMs where appropriate, improving clinician training, securing reimbursement, integrating PROMIS into clinical guidelines, and evaluating additional domains relevant to primary care physical therapy.

The study also reported a therapist quotation that captures the central implementation condition: "If the CAT can replace NPRS, PSFS, and Quebec while giving the same information, that's a win-win" (PT #6). Researchers should therefore analyze replacement value and workflow fit, not only perceived usability.

How Evidano Supports AI Qualitative Analysis in Healthcare

Problem: Mixed-methods evidence is spread across transcripts and spreadsheets

Evidano is an AI-powered qualitative data analysis platform that helps healthcare researchers analyze interviews, open-ended survey responses, and research documents.

Researchers can ingest interview transcripts, study papers, reports, and survey spreadsheets, then connect numerical response patterns with qualitative themes. Evidano's features include thematic, content, frequency, and cross-segment analyses that can support a workflow similar to the therapist-versus-patient comparison in the PLOS One study.

Problem: Important quotations are difficult to retrieve consistently

Evidano can help researchers search across source documents and analyses to locate participant language associated with concepts such as burden, relevance, score interpretation, portal access, and clinical usefulness.

Researchers should review every AI-retrieved quotation against the original transcript and preserve participant identifiers, context, and analytic decisions in the research record.

Problem: Stakeholder differences are easy to miss

Evidano can organize qualitative evidence by segment, such as patients, therapists, practice owners, or implementation managers, so researchers can compare whether the same issue appears differently across groups.

A cross-segment workflow could surface the divergence reported by the PLOS One study between therapists' perceptions of patient satisfaction and patients' own interview accounts.

Problem: Healthcare data requires careful handling

Healthcare research teams should use privacy-preserving workflows when analyzing interview transcripts and patient feedback. Evidano states that data is encrypted and never used to train third-party models; researchers can review the Evidano data security approach before selecting a platform.

AI-assisted analysis should support, not replace, human review, reflexivity, consent requirements, and the study's approved analytic protocol.

FAQ: AI Qualitative Analysis in Healthcare

What is AI qualitative analysis in healthcare?

AI qualitative analysis in healthcare uses artificial intelligence to organize, code, compare, and synthesize qualitative evidence such as interviews, open-ended survey responses, and clinical research documents.

AI can help identify recurring themes, retrieve quotations, compare stakeholder segments, and summarize large datasets, while qualified researchers remain responsible for interpretation, validation, and ethical oversight.

What did the 2026 PROMIS CAT study find?

The November 13, 2026 PLOS One study found that PROMIS CATs were generally feasible, acceptable, and useful in primary care physical therapy, but routine adoption was limited by duplicate PROMs, workflow issues, and uncertainty about score interpretation.

The study surveyed 25 therapists and interviewed 10 therapists plus 9 patients across 14 practices.

How were interviews analyzed in the PROMIS CAT study?

The PLOS One researchers used hybrid inductive-deductive thematic analysis with independent open coding, consensus meetings, disagreement documentation, and peer debriefing.

The researchers mapped themes onto Bowen's feasibility domains of acceptability, demand, practicality, and implementation.

Can AI replace human thematic analysis in healthcare research?

AI should not replace human thematic analysis in healthcare research because researchers must assess context, ambiguity, ethics, reflexivity, and whether interpretations are supported by the data.

AI can reduce repetitive organization and retrieval work, but researchers should validate codes and themes against source material and report the analytic process transparently.

What is the main implementation lesson from the PROMIS CAT findings?

The main implementation lesson is that PROMIS CATs should fit existing clinical workflows and replace unnecessary duplicate questionnaires rather than add to respondent burden.

The PLOS One study also identified clinician training, financial reimbursement, guideline support, and clearer access to item-level information as conditions for wider adoption.

Conclusion and Next Steps for Healthcare Researchers

The November 13, 2026 PLOS One study shows that PROMIS CATs can support efficient, patient-centered conversations in physical therapy, but feasibility alone does not guarantee routine implementation. The study's mixed-methods design also demonstrates why researchers need both numerical patterns and carefully analyzed participant voices to understand adoption barriers. AI qualitative analysis in healthcare can accelerate that synthesis by connecting transcripts, surveys, themes, quotations, and stakeholder segments while preserving human research oversight. Healthcare researchers can Try Evidano for free to analyze qualitative and mixed-methods data in one workspace.

Topics

  • AI qualitative analysis in healthcare
  • PROMIS CAT qualitative analysis
  • AI thematic analysis healthcare
  • mixed-methods healthcare research
  • patient-reported outcomes analysis

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